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2016 Vol. 69 No. 3

Original Basic Research And Clinical Articles2016-06-05
10.5173/ceju.2016.820
Evaluation of TKTL1 as a biomarker in serum of prostate cancer patients
Igor Tsaur, Kristina Thurn, Eva Juengel, Elsie Oppermann, Karen Nelson, Christian Thomas, Georg Bartsch, Gerhard M. Oremek, Axel Haferkamp, Peter Rubenwolf, Roman A. Blaheta
Monocyte associated transketolase-like 1 (TKTL1) as a cancer biomarker has become popular with alternative practitioners, but plays no role in conventional medicine. This investigation evaluates the potential of serum TKTL1 as a biomarker for prostate cancer.

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Review Paper2016-06-12
10.5173/ceju.2016.638
Uroplakins and their potential applications in urology
Michal Andrzej Matuszewski, Krzysztof Tupikowski, Łukasz Dołowy, Beata Szymańska, Janusz Dembowski, Romuald Zdrojowy
Urothelium is a highly specialized type of epithelium covering the interior of the urinary tract. One of the structures responsible for its unique features are urothelial plaques formed from glycoprotein heteropolymers, the uroplakins. Four types of uroplakins are known – UPIa, UPIb, UPII, UPIII. Herein we review the current status of knowledge about uroplakins and discuss their potential clinical applications.

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Review Paper2016-06-08
10.5173/ceju.2016.830
Role of angiogenesis in urothelial bladder carcinoma
Łukasz Piotr Fus, Barbara Górnicka
Bladder cancer is the most common urinary tract malignancy in western countries. In recent years, extensive research has suggested that angiogenesis plays an important role in bladder cancer biology, contributing to tumor growth and progression.

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Review Paper2016-06-08
10.5173/ceju.2016.832
Salvage local therapy for radiation-recurrent prostate cancer – where we are?
Romuald Zdrojowy, Janusz Dembowski, Bartosz Małkiewicz, Krzysztof Tupikowski, Wojciech Krajewski
Prostate cancer is the most frequent cancer among males in Europe and a leading cause of cancer deaths, with similar proportion in other developed countries. For more than twenty years, external-beam radiation therapy, alongside with radical prostatectomy, has been used as a primary radical therapeutic approach for localized prostate cancer. Yet, EBRT failures relate to 22–69% following curative radiotherapy (± androgen deprivation therapy). Additionally, a proportion of these men will have a biopsy-proven local recurrence.

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Case Report2016-08-23
10.5173/ceju.2016.854
Laparoscopic nephrectomy in a hemophilia B patient
Slawomir Gajda, Tomasz Szopiński, Andrzej B. Szczepanik, Roman Sosnowski, Anna M. Szczepanik
Surgery in patients with hemophilia is a serious challenge. We present here the first case of transperitoneal laparoscopic radical nephrectomy (TLRN) with adrenal gland saving for renal clear-cell carcinoma, performed in hemophilia B patient. The level of factor IX clotting activity before surgery and on postoperative days 1-6 was maintained at 65-130 % and at 30-0 % on subsequent days until post-operative wound healed. The intraoperative period and postoperative course was uneventful. In hemophilia patients the TLRN procedure requires proper preparation as well as adequate substitution therapy for the deficient coagulation factor provided by a multidisciplinary team in comprehensive center.

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Review Paper2016-06-13
10.5173/ceju.2016.819
Optimal management of lower pole stones: the direction of future travel
Sacha L. Moore, Ewa Bres-Niewada, Paul Cook, Hannah Wells, Bhaskar K. Somani
Kidney stone disease is increasing worldwide with its most common location being in the lower pole. A clear strategy for effective management of these stones is essential in the light of ever increasing choice, effectiveness, and complications of different treatment options.

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Original Basic Research And Clinical Articles2016-06-10
10.5173/ceju.2016.843
Effectiveness of 'on demand' silodosin in the treatment of premature ejaculation in patients dissatisfied with dapoxetine: a randomized control study
Gajanan S. Bhat, Anuradha Shastry
Premature ejaculation is a common sexual disorder, which is usually underreported. Multiple treatment methodologies are in use due to the absence of an effective, universally acceptable treatment modality. The most common drug used in this respect is dapoxetine, which also has adverse effects limiting its long-term use. Hence, we decided to evaluate the effectiveness of 'on demand' silidosin 4 mg in patients with premature ejaculation, who were dissatisfied with dapoxetine 30 mg.

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Case Report2016-07-21
10.5173/ceju.2016.838
The effect of seasonal variation on sexual behaviors in males and its correlation with hormone levels: a prospective clinical trial
Aslan Demir, Mehmet Uslu, Omer Erkam Arslan
The insertion of foreign bodies into the male urethra is not an uncommon urological presentation. Superglue is a material that can potentially cause significant complications if instilled into the urethra.
We describe a successful case of delayed (six months) removal of superglue from a 39 year old male's urethra having failed to remove the material at initial presentation.

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Review Paper2016-08-23
10.5173/ceju.2016.848
Surgical technique for the delayed removal of superglue from the male urethra
Matthew James Young, Timothy Noblet, Stephanie J. Symons
Social Media (SoMe) includes a broad spectrum of public use platforms like Twitter, Youtube or Facebook that have changed the way humans interact and communicate. Considering high usage rates for various SoMe platforms among urologists, we aimed to perform a review regarding opportunities, applications, appropriate use and new horizons of SoMe in urology.

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Editorial Referring
Social Media in Urology: opportunities, applications, appropriate use and new horizons
Juan Gómez Rivas, Moises Rodriguez Socarras, Leonardo Tortolero Blanco

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Author's Reply2016-07-25
10.5173/ceju.2016.894
Social Media - the growing role in urology
Roman Sosnowski, Artur Lemiński, Marc van Gurp

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10.5173/ceju.2016.872
Reply to: Sosnowski R, Lemiński A, van Gurp M. Social Media - the growing role in urology. Cent European J Urol. 2016; 69: 299-300.
Leonardo Tortolero Blanco, Juan Gómez Rivas, Moises Rodriguez Socarras

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Editorial Referring2016-08-09
10.5173/ceju.2016.872
LithoVue™: A new single-use digital flexible ureteroscope
Salvatore Butticč, Tarik Emre Sener, Christopher Netsch, Esteban Emiliani, Rosa Pappalardo, Carlo Magno

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Original Basic Research And Clinical Articles2016-06-17
10.5173/ceju.2016.833
Urological complications after renal transplantation - a single centre experience
Wojciech Krajewski, Janusz Dembowski, Anna Kołodziej, Bartosz Małkiewicz, Krzysztof Tupikowski, Michał Matuszewski, Paweł Chudoba, Maria Boratyńska, Marian Klinger, Romuald Zdrojowy
Urological complications after renal transplantation occur in between 2.5% and 30% of all graft recipients. The aim of the study was to present 7 years of experience in urological treatment of patients with a transplanted kidney. We aimed to identify retrospectively late urological complications in renal transplant recipients at a single center and analyze the treatment modalities and their outcome.

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Videosurgery2016-05-30
10.5173/ceju.2016.790
Transvesical laparoendoscopic single-site surgery (T-LESS) to remove an unusual foreign body from the bladder
Maciej Przudzik, Michał Borowik, Roman Łesiów, Zbigniew Purpurowicz, Marek Roslan
Foreign bodies in the bladder are quite common disorders of the lower urinary tract. Most of them originate from various surgical procedures but rarely are a consequence of transurethral self-insertion, as a result of sexual curiosity or autoerotic stimulation. From 2006 to 2015, in our center the prevalence of this condition was 0.05%, but only six (0.02%) of the cases were due to sexual curiosity. A standard 10-mm optic and straight laparoscopic instruments were used. Blood loss was minimal.

VIDEO PUBLICATION

Videosurgery2016-05-30
10.5173/ceju.2016.805
Laparoscopic calyceal diverticulectomy
Cristina Bonastre, Gabriel Briones
Calyceal diverticulum are  cystic cavities within renal parenchyma lined by nonsecretory epithelium and  communicating with  the  collecting system via a  narrow channel. Usually they are  asymptomatic and under one centimeter. The indications of surgical treatment are usually the symptomatic ones (hematuria, pain, infection), in  most cases associated with  the  calculi. The ultrasound and computed tomography (CT) showed a large upper pole renal abscess.

VIDEO PUBLICATION

Letter to the Editor2016-07-05
10.5173/ceju.2016.885
Ureteroscopy for stones in solitary kidney: Preferred not just a standard option
Patrick Jones, Bhavan Rai, Anngona Ghosh, Bhaskar K. Somani

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Dear Colleagues!

Please forgive me for this somewhat reflective mood, but it is caused by the up- coming end of the 2015-2018 term of the PUA Executive Board. As you probably know, the Editor-in-Chief of the Central European Journal of Urology is appointed by the PUA Executive Board, which is why this introductory article is somewhat of a summary.

So then, for this reason, I would like to share some information about the development of the journal. The journal is developing very well. When analyzing the names of the authors, we can see that we are recognizable not only in Europe but also around the world. Urologists from large academic centers publish their articles in our journal. We operate on an "open access" basis and therefore do not charge any fees. This is undoubtedly an asset. An expression of this is the growing number of our citations. The CiteScore coefficient for the Central European Journal of Urology is currently 1.11, while last year it was 0.70. The systematic increase in citations year by year sets the stage to move us from Emerging Cites Sources and promote us to the Science Citation Index Expanded, managed by Clarivate Analytics, formerly Thomson Reuters, which is associated with the granting of the socalled "Impact Factor". I first submitted our journal in 2015 and the assessment, at that time made by Thomson Reuters, was that we should remain in the "waiting room", and therefore we were included in Emerging Sources Citation Index. I submitted my second request for re-assessment at the end of 2017 and I am currently awaiting an answer. I hope to get a positive decision.

Building a urological journal in Europe is not a simple task. We already have journals of recognized position and reputation, such as European Urology, European Urology Focus, as well as World Journal of Urology, Urologia Internationalis, Scandinavian Journal of Urology and International Urology and Nephrology. There are also newly created journals such as European Urology Oncology which has very strong support from the European Association of Urology. We must show that we are needed in Central Europe! We do not have anything to prove!

The standing of a scientific journal depends firstly on the quality of the materials submitted, that is from the authors' workshops. However, this is only one side of the coin!

The team of people who verifies submitted scientific materials is also very crucial. This is probably the most important thing that I would like to convey. Usually, I do not officially direct words of thanks to my colleagues, because I think that they consciously chose the tasks they carry out in their lives. At this point, however, at the end of the 2015-2018 term of the PUA Executive Board, I would like to thank Dr. Bartosz Dybowski, my assistant Editor-in-Chief, for the enormous amount of work and time devoted to the extremely professional preparation of each issue. His ex- pert knowledge and availability could be the envy of many a manager. Without the hard work of Dr. Dybowski, this journal would not look like it does today, and the choice of his person for this position was certainly the right one.

I would also like to personally thank our section editors for their hard work and input. Przemysław Adamczyk, Ewa Bres-Niewada, Stefan Buntrock, Abdullah Erdem Canda, Michał Ciszek, Olga Dolejšová, Simona Di Francesco, Jan Hrbáček, Kajetan Juszczak, George Kasyan, Daimantas Milonas, Maciej Salagierski and Przemysław Waliszewski have always stood up to the task. Dear Colleagues, I know how much you have done for the journal, I appreciate it, and I will always remember your commitment.

Nothing could be done without the huge backing of internationally recognized professionals, without which the magazine would not be in the right form and would not grow. The Consulting Editors and the Editorial Board are these advisory bodies that I would like to thank for their knowledgeable comments and support in making difficult decisions.

Also, I would like to recognize the Reviewers, who often work "behind the scenes" but are nonetheless extremely helpful. Their complete independence allows them to give us their wise and unbiased opinions. Thank you for your support during the entire 2015-2018 term.

In conclusion, it is my sincere hope that the journal will continue to develop even better and even more vigorously in the coming years.


Tomasz Drewa
Editor-in-Chief

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Corrigendum
The Editorial Office would like to inform all interested parties that in Central European Journal of Urology an article entitled "Efficacy of holmium laser urethrotomy and intralesional injection of Santosh PGI tetra-inject (Triamcinolone, Mitomycin C, Hyaluronidase and N-acetyl cysteine) on the outcome of urethral strictures" [Kumar S, Kishore L, Sharma AP, Garg N, Singh SK. Cent European J Urol. 2015; 68: 462-465] was published which is very similar to the article entitled "Efficacy of Optical Internal Urethrotomy and Intralesional Injection of Vatsala-Santosh PGI Tri-Inject (Triamcinolone, Mitomycin C, and Hyaluronidase) in the Treatment of Anterior Urethral Stricture" published in Advances in Urology [Kumar S, Garg N, Singh SK, Mandal AK. Adv Urol. 2014; 2014: 192710. doi: 10.1155/2014/192710. Epub 2014 Oct 1].

The authors of these articles did not inform the CEJU Editorial Office about the prior publication of an article with a similar subject matter nor did they refer to it in their References section.

The Editorial Office regrets the existing situation.