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2015 Vol. 68 No. 2

Original Basic Research And Clinical Articles2015-02-01
10.5173/ceju.2015.528
Outcomes of partial nephrectomy in patients who meet percutaneous ablation criteria
Kelly T. Harris, Mark W. Ball, Michael A. Gorin, Mohamad E. Allaf, Phillip M. Pierorazio
Treatment options for small renal masses include partial nephrectomy (PN), ablation and active surveillance. We sought to compare patients who met criteria for percutaneous ablation but underwent robotic PN to the rest of our robotic PN cohort. This was done in order to detect any safety concerns and to define any risk factors that might contraindicate the use of robotic PN, an oncologically superior procedure, in patients who qualify for ablation.

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Editorial Referring10.5173/ceju.2015.e99
What matters when selecting candidates for renal ablation: tumor size or the patient's condition?
Pilar M. Laguna

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Editorial Referring10.5173/ceju.2015.e103
Can robotic partial nephrectomy replace the ablati e techniques in the treatment of small renal masses?
Alin Adrian Cumpanas

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Author's Reply10.5173/ceju.2015.r102
Reply to: Laguna PM. What matters when selecting candidates for renal ablation: tumor size or patient's condition? Cent European J Urol. 2015; 68: 137-138, and: Cumpanas AA. Can robotic partial nephrectomy replace the ablative techniques in the treatment of small renal masses? Cent European J Urol. 2015; 68: 139
Kelly T. Harris, Mark W. Ball, Phillip M. Pierorazio

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Original Basic Research And Clinical Articles2014-11-06
10.5173/ceju.2015.475
Survival up to 5-15 years in young women following genital sparing radical cystectomy and neobladder: oncological outcome and quality of life. Single-surgeon and single-institution experience
Mohamed Wishahi, Hossam Elganozoury
This is an observational retrospective study utilising long term patient follow-up for 15 years to determine the survival and quality of life in women (age range 20-5 years) after having been treated for carcinoma of the bladder by radical cystectomy with preservation of genital organs.

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Editorial Referring10.5173/ceju.2015.e102
Sparing radical cystectomy - How much is enough?
Christian Schwentner

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Author's Reply10.5173/ceju.2015.r101
Reply to: Schewentner C. Sparing radical cystectomy - How much is enough? Cent European J Urol. 2015; 68: 146
Mohamed Wishahi

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Original Basic Research And Clinical Articles2015-04-08
10.5173/ceju.2015.610
External validation of extended prostate biopsy nomogram
Jan Hrbáček, Ivo Minárik, Tomáš Sieger, Marek Babjuk
Historical nomograms for the prediction of cancer on prostate biopsy, developed in the sextant biopsy era are no more accurate today. The aim of this study was an independent external validation of a 10-core biopsy nomogram by Chun et al. (2007).

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Review Paper2015-04-17
10.5173/ceju.2015.571
Extrarenal nephroblastoma
Wojciech Apoznański, Krystyna Sawicz-Birkowska, Mateusz Palczewski, Tomasz Szydełko
Nephroblastoma is one of the most common solid tumours in children. The occurrence of the extrarenal nephroblastoma is exceedingly rare. What can be defined as extrarenal Wilm's tumour must satisfy the following criteria: histologically confirmed nephroblastoma and extrarenal location.

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Review Paper2015-02-20
10.5173/ceju.2015.453
The role of epigenetics in kidney malignancies
Alfredo Harb, Matthew Acker, Sanjaya Swain, Murugesan Manoharan
Renal cell carcinomas (RCC) are collectively the third most common type of genitourinary neoplasms, surpassed only by prostate and bladder cancer. Cure rates for renal cell carcinoma are related to tumor grade and stage, therefore, diagnostic methods for early detection and new therapeutic modalities are of paramount importance. Epigenetics can be defined as inherited modifications in gene expression that are not encoded in the DNA sequence itself. Epigenetics may play an important role in the pursuit of early diagnosis, accurate prognostication and identification of new therapeutic targets.

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Review Paper2015-02-01
10.5173/ceju.2015.513
Contemporary hormone therapy with LHRH agonists for prostate cancer: avoiding osteoporosis and fracture
Hannah C.P. Wilson, Jacek Andruszkiewicz, Paul D. Abel, Patricia Price, Lesley Honeyfield, Steve Edwards, Richard L. Abel
Prostate cancer is a large clinical burden across Europe. It is in fact the most common cancer in males accounting for more than 92,300 deaths annually throughout the continent. Prostate cancer is androgen sensitive; thus an androgen deprivation therapy (ADT) is often used for treatment by reducing androgen to castrate levels. Several ADT agents have achieved benefits with effective palliation but unfortunately severe adverse events are frequent. Contemporary ADT (i.e. Luteinising Hormone Releasing Hormone agonist - LHRHa injections) can result in side effects that include osteoporosis and fracture, compromising quality of life and survival

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Original Basic Research And Clinical Articles2015-01-04
10.5173/ceju.2015.507
The effect of complete transurethral resection of the prostate on symptoms, quality of life, and voiding function improvement
Daimantas Milonas, Jone Verikaite, Mindaugas Jievaltas
Transurethral resection of the prostate (TURP) still remains most popular surgical treatment for patients with lower urinary tract symptoms. However, in some patients, the improvement of symptoms after TURP is insufficient. The aim of our study was to evaluate the impact of the resected prostate tissue weight (RPTW) on the improvement of symptoms (IPSS), quality of life (QoL), and voiding function after TURP.

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Review Paper2015-04-17
10.5173/ceju.2015.537
The role of lasers in modern urology
Łukasz Dołowy, Wojciech Krajewski, Janusz Dembowski, Romuald Zdrojowy, Anna Kołodziej
The functioning of modern urological departments and the high level of service they provide is possible through, among other things, the use of modern laser techniques.

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Original Basic Research And Clinical Articles2015-02-05
10.5173/ceju.2015.509
Is flexible ureterorenoscopy and laser lithotripsy the new gold standard for lower pole renal stones when compared to shock wave lithotripsy: Comparative outcomes from a University hospital over similar time period
Jacob Burr, Hiro Ishii, Nick Simmonds, Bhaskar K. Somani
Renal lower pole stones pose difficulty in management due to anatomical variation, stone size, hardness and patient demographics. Flexible ureterorenoscopy and laser lithotripsy(FURSL) and shock wave lithotripsy(SWL) are preferred for stones 1-2cm in size. We wanted to compare the outcomes of FURSL and SWL for lower pole stones during the same time period.

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Original Basic Research And Clinical Articles2015-04-08
10.5173/ceju.2015.538
Combined ureterorenoscopy for ureteral and renal calculi is not associated with adverse outcomes
Erdal Alkan, Mirac Turan, Ahmet Oguz Ozkanli, Egemen Avci, Mehmet Murad Basar, Oguz Acar, Mevlana Derya Balbay
We intented to evaluate the feasibility and effectiveness of simultaneous rigid and flexible ureteroscopic treatment of symptomatic ureteral and ipsilateral small simultaneous calyceal stones. Outcomes of combined therapy were compared with monotherapy alone.

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Original Basic Research And Clinical Articles2015-04-02
10.5173/ceju.2015.533
Feasibility and safety of bilateral same-session flexible ureteroscopy (FURS) for renal and ureteral stone disease
Tamsin Drake, Ahmed Ali, Bhaskar K. Somani
With rising incidence of urolithiasis, treatment of stones (both symptomatic and asymptomatic) in multiple locations including bilateral stones can be controversial and challenging. We report our experience and treatment outcomes in patients undergoing bilateral, same-session ureterorenoscopy (BS-URS) for bilateral ureteric and/or renal calculi, and discuss the advantages and disadvantages of such procedures.

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Editorial Referring10.5173/ceju.2015.e100
More aggressive intrarenal endoscopic maneuvers are assuring a stone free outcome and safety
Artur A. Antoniewicz

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Author's Reply10.5173/ceju.2015.r100
Reply to: Antoniewicz A A. More aggressive intrarenal endoscopic maneuvers are assuring a stone free outcome and safety. Cent European J Urol. 2015; 68: 197 -198
Erdal Alkan, Mevlana Derya Balbay

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Author's Reply10.5173/ceju.2015.r99
Reply to: Antoniewicz AA. More aggressive intrarenal endoscopic maneuvers are assuring a stone free outcome and safety. Cent European J Urol. 2015; 68: 197-198
Bhaskar K. Somani

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Original Basic Research And Clinical Articles2015-02-02
10.5173/ceju.2015.479
Pain control using pethidine in combination with diazepam compared to diclofenac in combination with hyoscine-n-butyl bromide: in patients undergoing extracorporeal shock wave lithotripsy
Aslan Demir, Kursat Cecen, Mert Ali Karadag, Mehmet Uslu, Omer Erkam Arslan
Extracorporeal Shock Wave Lithotripsy (ESWL) remains the preferred least invasive treatment for urinary tract stones. The main purpose of this study was to compare two treatment modalities for pain control during the ESWL procedure.

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Short Communications (Preliminary Results And Mini-Reviews)2015-02-20
10.5173/ceju.2015.522
The current role of simulation in urological training
Ryan Preece
Simulation is becoming an increasingly popular educational tool in numerous surgical specialities, including urology. This article reviews the current role of urological simulators; discussing their need, availability, incorporation and current limitations.

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Editorial Referring10.5173/ceju.2015.e101
The 'complements' to virtual simulation
Juan Gómez Rivas, Selçuk Sarikaya

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Editorial Referring10.5173/ceju.2015.e98
Simulation - the need for a paradigm shift in urological training
Krish Sairam

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Original Basic Research And Clinical Articles2015-01-27
10.5173/ceju.2015.484
Improvement in sexual function after robot-assisted radical prostatectomy: A rehabilitation program with involvement of a clinical sexologist
Christina Ljunggren, Peter Ströberg
To prospectively evaluate if the inclusion of a clinical sexologist in a penile and sexual rehabilitation program improves sexual function one year after prostate cancer surgery

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Editorial Referring10.5173/ceju.2015.e97
Sexual rehabilitation or penile rehabilitation - do we have an optimal post-prostatectomy regimen?
Marta Skrodzka

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Original Basic Research And Clinical Articles2015-04-24
10.5173/ceju.2015.608
Transrectal-ultrasound prostatic biopsy preparati rectal enema vs. mechanical bowel preparation
Cosimo De Nunzio, Riccardo Lombardo, Fabrizio Presicce, Mariangela Bellangino, Enrico Finazzi Agro, Matteo Bonetto Gambrosier, Alberto Trucchi, Stefano Petta, Andrea Tubaro
Trans-rectal prostate biopsy (TRUSbx) is the standard in the diagnosis of prostate cancer. Different bowel preparations are used for patients undergoing TRUSbx. Aim of our study was to compare two different bowel preparations for TRUSbx.

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Short Communications (Preliminary Results And Mini-Reviews)2015-02-18
10.5173/ceju.2015.531
A single 80 mg intravenous gentamicin dose prior to prostate needle biopsy does not reduce procedural infectious complications
Jay D. Raman, Chris Rjepaj, Christopher Otteni
Rates of infectious complications continue to rise following transrectal ultrasound guided prostate needle biopsy (TRUS PNB). Administration of a parenteral antibiotic at time of procedure represents one potential prophylaxis strategy. The efficacy of this practice remains incompletely defined.

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Original Basic Research And Clinical Articles2015-04-25
10.5173/ceju.2015.584
Santosh PGI pouch: A new innovation in urinary diversion
Santosh Kumar, Sudheer Kumar Devana, Aditya Prakash Sharma, Shrawan Kumar Singh
To know the feasibility and outcome of Santosh PGI pouch as a new innovative technique of continent cutaneous diversion (CCD) following cystectomy

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Original Basic Research And Clinical Articles2015-03-09
10.5173/ceju.2015.562
Robot-assisted laparoscopic total extraperitoneal hernia repair during prostatectomy: technique and initial experience
Hasan A.R. Qazi, Bhavan Rai, Minh Do, Matthew Rewhorn, Tim Häfner, Evangelos Liatsikos, Panagiotis Kallidonis, Anja Dietel, Jens Uwe Stolzenburg
To describe the technique of Total Extraperitoneal inguinal hernia repair performed during Robot-assisted Endoscopic Extraperitoneal Radical Prostatectomy (R-EERPE) and to present the initial outcomes.

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Review Paper2015-04-18
10.5173/ceju.2015.543
An up-to-date overview of minimally invasive treatment methods in ureteropelvic junction obstruction
Rahmi Gokhan Ekin, Orcun Celik, Yusuf Ozlem Ilbey
Over the last two decades, minimally invasive treatment options for ureteropelvic junction obstruction (UPJO) have been developed and they have become popularized. Multiple series of laparoscopic pyeloplasty have demonstrated high success rates and low perioperative morbidity in pediatric and adult populations, with both the transperitoneal and retroperitoneal approaches. A larger number of cases have also been reported for adult patients, confirming that robotic pyeloplasty represents a viable option for either primary or secondary repair

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Original Basic Research And Clinical Articles2015-04-07
10.5173/ceju.2015.542
Is it possible to distinguish testicular torsion from other causes of acute scrotum in patients who underwent scrotal exploration? A multi-center clinical trial
Mustafa Güneş, Mehmet Umul, Muammer Altok, Mehmet Akyüz, Cemal Selcuk Isoglu, Fatih Uruç, Bekir Aras, Zülfü Sertkaya, Ahmet Urkmez, Ercan Baş, Muzaffer Oguz Keleş
To assess the clinical presentation of patients who underwent surgical exploration for acute scrotum and to investigate the potential related factors for differential dignosis.

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Original Basic Research And Clinical Articles2015-03-03
10.5173/ceju.2015.493
EVC gene polymorphisms and risks of isolated hypospadias - a preliminary study
Andrzej Kowal, Adrianna Mostowska, Dariusz Mydlak, Bożena Eberdt-Gołąbek, Matthew Misztal, Paweł P. Jagodzinski, Kamil K. Hozyasz
Hypospadias has a complex etiology with both genetic and environmental factors contributing to the condition. Urogenital abnormalities including hypospadias, are found in 22% of cases with Ellis van Creveld syndrome (EvC). Mutations in EVC gene can cause major and minor anomalies, which form phenotypes that partially overlap with EvC.
The aim of this study was to evaluate the association between nucleotide variants of EVC gene and the risk of hypospadias.

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Videosurgery2015-04-02
10.5173/ceju.2015.566
Robotic adrenalectomy for a 3 cm sized left adrenal mass suggesting Cushing's syndrome
Abdullah Erdem Canda
In this video, a case of Cushing's syndrome due to 3 cm sized left adrenal mass treated by left robotic adrenalectomy (RA) is presented. A 33-year old female patient who was diagnosed with Cushing's syndrome at another center due to the presence of a 3 cm sized left adrenal mass lesion was referred to our institution for robotic surgery. Preoperative pituitary magnetic resonance imaging (MRI) was within normal limits. Abdominal ultrasound and MRI showed a 3 cm sized left adrenal lesion.

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