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2013 Vol. 66 No. 4

Review Paper2013-11-08
10.5173/ceju.2013.04.art2
Renal Cell Carcinoma: How To Hit The Targets?
Oleg Banyra, Marjan Tarchynets, Alexander Shulyak
Renal cell carcinoma (RCC) is a widespread oncourological disease with a tendency towards to slow increasing of incidence. In the recent decade, have been appeared numerous effective drugs targeted on different molecules that play a dominant role in RCC carcinogenesis. Understanding of RCC carcinogenesis confirms the key role of angiogenesis in maintaining the viability of renal tumours and their metastases.

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Original Basic Research And Clinical Articles2013-10-24
10.5173/ceju.2013.04.art3
MMP7 and MMP8 genetic polymorphisms in bladder cancer patients
Edyta Wieczorek, Edyta Reszka, Wojciech Wasowicz, Adam Grzegorczyk, Tomasz Konecki, Marek Sosnowski, Zbigniew Jablonowski
Breakdown of the extracellular matrix by matrix metalloproteinases (MMPs) as we know is one of mechanisms involved and required in the tumor invasion. MMP7 is a negative prognostic factor of various malignances, while MMP8 exhibits an inhibitory effect on tumorigenesis and metastasis. We evaluated the potential association of functional polymorphisms in the promoter of the MMP7 (rs11568818) and MMP8 (rs11225395) genes and bladder cancer (BC) risk.

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Editorial Referring10.5173/ceju.2013.04.art4
The genetic patterns of bladder cancer. Where do we stand now?
Maciej Salagierski

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Review Paper2013-11-25
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Cajal-like interstitial cells as a novel target in detrusor overactivity treatment: true or myth?
Kajetan Juszczak, Piotr Maciukiewicz, Tomasz Drewa, Piotr J. Thor
The Cajal-like intestitial cells (ICCs) act as a pacemakers and are responsible for generating smooth muscle activity in the gastrointestinal tract (GI). Interstitial cells that resemble ICCs in GI have been identified in the urinary bladder.

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Review Paper2013-10-02
10.5173/ceju.2013.04.art6
The value of EORTC risk tables in evaluating recurrent non-muscle-invasive bladder cancer in everyday practice.
Rafał Walczak, Krzysztof Bar, Janusz Walczak
Due to the risk of recurrence and progression, patients with non-muscle-invasive bladder cancer have to be under observation. The aim of this study is the evaluation of early recurrence at the first control cystoscopy, as a prognostic factor for recurrence and progression based on EORTC risk tables.

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Original Basic Research And Clinical Articles2013-09-22
10.5173/ceju.2013.04.art7
Obesity, diabetes and aggressive prostate cancer hormone-naive at initial diagnosis
Simona di Francesco, Raffaele L. Tenaglia
Epidemiologic studies have implicated obesity in prostate cancer (PCa) development and aggressiveness, nevertheless no clear consensus has been reached. Aim of research was to investigate the association of obesity with PCa hormone-naïve at initial diagnosis.

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Editorial Referring10.5173/ceju.2013.04.art8
Obesity and prostate cancer research
Thomas Van den Broeck, Lorenzo Tosco, Stefan Prekovic, Steven Joniau

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Author's Reply10.5173/ceju.2013.04.art9
Author's reply
Simona di Francesco, Raffaele L. Tenaglia

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Case Report2013-10-02
10.5173/ceju.2013.04.art10
Tumor growth in intestinal neobladder - A Case Report
Wojciech Jerzy Skrodzki, Jarosław Głuchowski, James Weli-Wegbe, Adam Blawat, Janusz Kordasz
The case of a 73 years old man with tumor in intestinal neobladder was presented. Tumor was resected using standard TUR technique. Tumor proved to be benign, follow-up revealed no recurrences. The schedule of lifelong follow-up was proposed.

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Case Report2013-11-06
10.5173/ceju.2013.04.art11
Kidney angiomyolipoma in pregnancy - case report.
Krzysztof Tupikowski, Aleksander Biały, Janusz Dembowski, Monika Złotkiewicz, Maciej Guziński, Anna Karina Kołodziej, Romuald Zdrojowy
Neoplasms are rare in pregnant women and always are a challenging diagnostic and curative problem. We present a case of a benign kidney tumor imitating nephroblastoma on magnetic resonance diagnosed in pregnancy. Cesarean section was performed in 29. gestotic week followed immediately by right radical nephrectomy.

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Case Report2013-11-14
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A spontaneous paraganglioma-pheochromocytoma syndrome - case report
Sadegh Toutounchi, Ryszard Pogorzelski, Maciej Siński, Izabela Łoń, Łukasz Zapała, Patryk Fiszer, Ewa Krajewska, Maciej Skórski
We present a case of a 0-year old woman diagnosed with a four-place spontaneous paraganglioma-pheochromocytoma syndrome treated surgically. The presence of SDHD mutation that causes the pheochromocytoma was confirmed but no mutation in family members was found. After the excision of paragangliomas located in the areas of the division of carotid arteries, and mediastinum, as well as a tumor on the left site of the celiac trunk, the patient remains asymptomatic and is regularly followed-up.

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Original Basic Research And Clinical Articles2013-09-12
10.5173/ceju.2013.04.art13
APPROACH OF KIDNEY STONES ASSOCIATED WITH URETEROPELVIC JUNCTION OBSTRUCTION DURING LAPAROSCOPIC PYELOPLASTY.
Juan Gómez Rivas, Sergio Alonso y Gregorio, Leslie Cuello Sánchez, Cristina de Castro Guerin, Luis Hidalgo Togores, Jesús Javier de la Pena Barthel
We perform laparoscopic pyeloplasty (LP) in our department since 200. Our goal is to describe step by step the approach of kidney stones during transperitoneal laparoscopic pyeloplasty and the outcomes after the procedure.

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Editorial Referring10.5173/ceju.2013.04.art14
Laparoscopic pyeloplasty with concomitant pyelolithotomy - too much of a good thing?
Marcin Słojewski

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Author's Reply10.5173/ceju.2013.04.art15
The evolution of the treatment of urinary stone disease
Juan Gómez Rivas, Sergio Alonso y Gregorio

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Original Basic Research And Clinical Articles2013-09-11
10.5173/ceju.2013.04.art16
CHOICE OF SURGICAL ACCESS FOR RETROPERITONEOSCOPIC URETEROLITHOTOMY ACCORDING TO THE RESULTS OF 3D RECONSTRUCTION OF OPERATIONAL ZONE AGREED WITH THE PATIENT: INITIAL EXPERIENCE
Vasilii N. Dubrovin, Valerii I. Bashirov, Yakov A. Furman, Alexey A. Rozhentsov, Ruslan V. Yeruslanov, Alexandr A. Kudryavtsev
The problem of choosing minimally invasive surgical access for gasless single port or with gas insufflation retroperitoneoscopic ureterolithotomy is solved. The decision is based on the method of presurgery planning grounded on matching the patient with a 3D model of the zone of surgical interest reconstructed according to the results of tomographic examination.

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Editorial Referring10.5173/ceju.2013.04.art17
Virtual guidance of urologic surgery
Jakub Dobruch

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Editorial Referring10.5173/ceju.2013.04.art18
Do we really always need gimmicks?
Stanisław Wroński

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Original Basic Research And Clinical Articles2013-08-22
10.5173/ceju.2013.04.art19
OUR EXPIENCE IN MANAGEMENT OF LOWER URETERIC STONES: A PROSPECTIVE STUDY
Mohamed Etafy, Gamal A.M. Morsi, Mansour S.M. Beshi, Sheri S. Soliman, Hussein A. Galal, Cervando Ortiz-Vanderdys
to discuss the current concepts in lower ureteric stones management.

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Editorial Referring10.5173/ceju.2013.04.art20
URS versus ESWL: another contribution to the never-ending debate
Jan Hrbáček

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Editorial Referring10.5173/ceju.2013.04.art21
Large impacted distal ureteric stonnes is better treated by URS: putting priorities
Vigen Malkhasyan, Dmitri Pushkar

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Review Paper2013-10-30
10.5173/ceju.2013.04.art22
Psychotropics and Sexual dysfunction
Anthony J. Bell, Rany Shamloul
Sexual dysfunction (SD) is a common condition in patients taking antipsychotics, and is the most bothersome symptom and adverse drug effect, resulting in a negative effect on treatment compliance. Mechanisms involved in psychotropics-induced SD are largely unknown or poorly understood.
Aim: The aim of this review is to present an updated analysis of SD associated with the use of psychotropic drugs in psychiatric patients.

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Original Basic Research And Clinical Articles2013-09-11
10.5173/ceju.2013.04.art23
Disturbances of trace elements metabolism in ESRD patients receiving hemodialysis and hemodiafiltration
Mykola Prodanchuk, Oleksii Makarov, Evegnii Pisarev, Boris Sheiman, Mykola Kulyzkiy
Accumulation of trace elements occurs in conditions of kidneys functions decrease. In some conditions increased trace elements can have toxic features. On the other hand, researches are showing that concentration of some trace elements could be decreased in ERSD patients, too. The most important factor affecting trace element concentration in ERSD patient is the degree of renal failure and using of replacement therapy.

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Original Basic Research And Clinical Articles2013-11-12
10.5173/ceju.2013.04.art24
Experiences with the Management of Paraurethral Cysts in Adult Women
Osman Köse, Hüseyin Aydemir, Osman Metin, Salih Budak, Adil Sonbahar, Öztug Adsan
Paraurethral cysts may be acquired or congenital pathology, and are rarely encountered in urogynecologic practice. Therefore, no consensus on management of paraurethral cyst could be reached. We aimed to report our experience on the management of paraurethral cysts in adult women.

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Original Basic Research And Clinical Articles2013-08-28
10.5173/ceju.2013.04.art25
Continent ileovesicostomy after bladder neck closure as salvage procedure for intractable incontinence
Jennifer Kranz, Petra Anheuser, Steffen Rausch, Guido Fechner, Moritz Braun, Stefan C. Müller, Joachim A. Steffens, Tilman Kälble
We evaluated the success rate of continent vesicostomy using an ileal segment with seroserosally embedded, tapered ileum for bladder augmentation with continent stoma following bladder neck closure (BNC) for severely damaged bladder or persistent urinary incontinence.

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Editorial Referring10.5173/ceju.2013.04.art26
Salvage procedures in reconstructive urology
Roger Dmochowski

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Review Paper2013-08-27
10.5173/ceju.2013.04.art27
Bougie urethral dilators; revival or survival?
Atif Abdulhamid Katib, Mohammad Ahmad Al-Adawi
To present our center's experience in managing bladder outlet obstruction (BOO) conditions using bougie dilators. We described the dilation technique methodically for teaching purpose.

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Editorial Referring10.5173/ceju.2013.04.art28
The initial treatment of urethral strictures: simple dilatation or urethrotomy? "Bougie urethral dilators; revival or survival?" - pros opinion
Ewa Bres-Niewada

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Editorial Referring10.5173/ceju.2013.04.art29
"Bougie urethral dilators; revival or survival?" - cons opinion
Wojciech Perdzyński

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Case Report2013-10-12
10.5173/ceju.2013.04.art30
Foreign body in the kidney: an unusual case and its management
Dharam Vir Singh, Yogesh K. Swami, Yajvender Pratap Singh Rana, Shafi M. Wani
Foreign body (FB) in kidney is uncommon. Most of the time a FB is introduced externally (violence or accident) or through endourological interventions. Ingested FB reaching the kidneys is extremely rare. We report an interesting case of FB, which apparently reached the kidney through gastrointestinal tract and briefly review the relevant literature. The case was successfully managed laparoscopically.

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Dear Colleagues,

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