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2013 Vol. 66 No. 3

Original Basic Research And Clinical Articles2013-06-05
10.5173/ceju.2013.03.art2
Inflammatory changes in biopsy specimens from patients with suspected prostate cancer
Przemysław Adamczyk, Zbigniew Wolski, Romuald Butkiewicz, Joanna Nussbeutel, Tomasz Drewa
Prostate cancer (PCa) is one of the most commonly diagnosed cancers in elderly men. The development of the 'clinically insignificant' prostate cancer into its invasive form is still unclear, and it is believed, that chronic inflammation may play its role, what was proposed by De Marzo in 1999. But there is no clear opinion on the subject of existence of dependencies between changes of the inflammatory type and PCa.

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Editorial Referring10.5173/ceju.2013.03.art3
Inflammatory changes and the prostate
Mark S. Soloway

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Author's Reply10.5173/ceju.2013.03.art4
Author's reply
Przemysław Adamczyk

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Original Basic Research And Clinical Articles2013-08-20
10.5173/ceju.2013.03.art5
Lymphovascular invasion in testicular germ cell tumors: clinical - pathological correlates
Ofer Yossepowitch, Yaron Ehrlich, Marc Lubin, Raanan Tal, Miriam Konichezsky, Jack Baniel
We assessed clinical-pathological correlates of lymphovascular invasion in testicular germ-cell tumors

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Editorial Referring10.5173/ceju.2013.03.art6
Precise pathological assessment plays a key role in proper patient management in non-seminoma germ cells tumor
Roman Sosnowski, Marcin Ligaj

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Review Paper2013-08-20
10.5173/ceju.2013.03.art7
The Relationship of Cancer Stem Cells in Urological Cancers
Jan Adamowicz, Marta Pokrywczyńska, Jakub Tworkiewicz, Zbigniew Wolski, Tomasz Drewa
Numerous studies are ungoing to identify and isolate cancer stem cells from cancers of genito-urinary tracts . The better understanding of their role in prostate, urothelial and kidney cancer origin, growth and progression opens new pathways in development of more effective treatment methods. However there are still many issues before advances in this field can be introduced for clinical application. This review addresses current achievements in cancer stem cells research in uro-oncology.

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Editorial Referring10.5173/ceju.2013.03.art8
Stem cells - the key to cancer treatment
Kajetan Juszczak, Piotr Maciukiewicz

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Original Basic Research And Clinical Articles2013-08-01
10.5173/ceju.2013.03.art9
PROGNOSTIC FACTORS OF OVERALL SURVIVAL IN RENAL CANCER PATIENTS - SINGLE ONCOLOGICAL CENTER STUDY
Tomasz Drewniak, Marek Sandheim, Jacek Jakubowski, Kajetan Juszczak, Andrzej Wojciech Stelmach
The clinical course of renal cancer remains difficult to predict. Attempts of appointing new Independent Prognostic Factors (IPFs) and comparisons of already identified ones among populations are inevitable to develop more effective prognostic instruments. The aim of the study was to evaluate IPFs of overall survival in given population of patients with renal cancer.

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Case Report2013-05-16
10.5173/ceju.2013.03.art10
Repeated Endoscopic Treatments of Multiple Recurrent Ureteral Tumors Following 5-Year-Long History of Bladder Tumors in the Patient from Endemic Nephropathy Region
Tomislav Pejcic, Jovan Hadzi-Djokic, Biljana Markovic, Zoran Dzamic, Ljubomir Djurasic, Miodrag Acimovic
Ureteral urothelial tumors (UUT) are uncommon; the incidence is higher in areas of Balkan endemic nephropathy (BEN), with the prevalence of low grade lesions. In these patients, the efficacy of conservative surgery is comparable to nephroureterectomy. Endoscopic treatment is indicated for single, small/low grade UUT, in older patients with significant comorbidity.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Case Report2013-06-05
10.5173/ceju.2013.03.art11
Rare Case of Malignant Lymphoma of Kidney
Maciej Ziarek, Marek Długosz, Marek Lipiński
We present a 6-year-old patient suffering from extranodal malignant lymphoma. The patient was admitted to the County Hospital Urology Ward with suspicion of the left kidney tumour. As a part of pre-operational diagnosis, ultrasonographic examination and computed tomography of kidneys were conducted. The results confirmed the initial diagnosis. After undergoing radical surgical treatment, the patient is currently under the care of hematology ward of oncology centre.

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Case Report2013-05-16
10.5173/ceju.2013.03.art12
Retroperitoneoscopic renal pelvis resection as a treatment of the urothelial tumor of the solitary kidney
Mateusz Wojtarowicz, Marcin Słojewski, Adam Gołąb, Piotr Petrasz
Urothelial carcinoma of the upper urinary tract is relatively rare. The standard treatment is invariably radical nephroureterectomy. In selected cases organ sparing surgery is justified. We present the case of the tumor of the kidney pelvis of the solitary organ where a laparoscopic approach was successfully applied.

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Original Basic Research And Clinical Articles2013-06-23
10.5173/ceju.2013.03.art13
Conventional Monopolar Transurethral Resection of Prostate in Patients with Large Prostate (≥80 grams)
Mehmet Yucel, Bekir Aras, Soner Yalcinkaya, Namik Kemal Hatipoglu, Erol Aras
Transurethral resection of the prostate (TURP) is still regarded as the gold standard for the treatment of lower urinary tract symptoms (LUTS) secondary to benign prostate obstruction in prostates between 30 and 80 mL. Endoscopic treatment of large prostate is not adequately discussed in literature. Our objective was to evaluate the efficacy and safety of TURP in large prostate glands (>80 ml) in patients with BPH.

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Original Basic Research And Clinical Articles2013-07-05
10.5173/ceju.2013.03.art14
Double J stent reduces the efficacy of extracorporeal shock wave lithotripsy in the treatment of ureteral lumbar stones
Caroline Pettenati, Amine Benchikh El Fegoun, Vincent Hupertan, Sébastien Dominique, Vincent Ravery
We evaluated the effect of the presence of a double J stent on the efficacy of extracorporeal shock wave lithotripsy (ESWL) in the treatment of ureteral lumbar stones.

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Editorial Referring10.5173/ceju.2013.03.art15
Is there a place for ESWL in the treatment of complicated proximal ureteral stones?
Ewa Bres-Niewada

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Original Basic Research And Clinical Articles2013-05-24
10.5173/ceju.2013.03.art16
CORRECTION OF FERTILITY DISORDERS IN PATIENTS WITH CRYOGLOBULINEAMIA
Borys Gerasun, Roman Kopets, Roman Hrytsko, Oleksandr Herasun
Cryoglobulinemia can be among the causes of sperm bad quality. But conventional examination algorithm for patients with idiopathic oligozoospermia makes no provision for cryoglobulin determination in blood serum.

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Original Basic Research And Clinical Articles2013-05-01
10.5173/ceju.2013.03.art17
Asymptomatic Bacteriuria in Postmenopausal Women with Diabetes Mellitus
George Kasyan, Tatiana Y. Berketova, Anton K. Rogozin, Dmitry Y. Pushkar
An evaluation of efficacy of the management of urinary tract infections by using local forms of Estriol in postmenopausal women with type 2 diabetes and asymptomatic bacteriuria.

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Editorial Referring10.5173/ceju.2013.03.art18
Are the estrogens an effective umbrella against bacterial bladder invasion?
Jerzy B. Gajewski

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Editorial Referring10.5173/ceju.2013.03.art19
Editorial referring to the paper published in this issue on pp. 320-326
Thorsten H. Ecke

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Editorial Referring10.5173/ceju.2013.03.art20
Urinary tract infections in postmenopausal women
Sotir Stavridis

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Author's Reply10.5173/ceju.2013.03.art21
Author's reply
George Kasyan

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Letter to the Editor2013-05-17
10.5173/ceju.2013.03.art22
A three year review of the management of Fournier's gangrene presenting in a single Saudi Arabian institute
Atif Katib, Mohammad Al-Adawi, Bassem Dakkak, Amani Bakhsh

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Editorial Referring10.5173/ceju.2013.03.art23
Towards zero mortality in Fournier's gangrene
Bolesław Kuzaka, Bartosz Dybowski

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Case Report2013-08-11
10.5173/ceju.2013.03.art24
Gangrene of the penis, scrotum and perineum, occurred after radiotherapy of rectal cancer - a case report
Marcin Życzkowski, Rafał Bogacki, Piotr Bryniarski, Krzysztof Nowakowski, Bartosz Muskała, Andrzej Paradysz
We present a case of a 58-old man hospitalized because of a gangrene of the penis and scrotum, after radio-chemotherapy for rectum cancer. At the time of the adoption patients presented with extensive gangrene with necrosis affecting the scrotum and the penis. In the first day of hospitalization the patient was operated. Due to the progress of the disease, he had to be operated again. The status of the patient initially very bad, was gradually improving. He was discharged from hospital after 59 days in good general status with good wound healing.

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Case Report2013-05-19
10.5173/ceju.2013.03.art25
The Remnant of Congenital Blind- Ended Megaureter in 23-Year-Old Woman Causing Chronic Pain and Urinary Infection
Tomislav Pejcic, Biljana Markovic, Zoran Dzamic, Milan Radovanovic, Jovan Hadzi-Djokic
Multicystic dysplastic kidney (MCDK) is congenital anomaly as the result of abnormal interaction between the ureteric bud and metanephric mesenchyme. Unilateral MCDK can be associated with other anomalies of the genitourinary tract. Relatively rare associated anomaly is the presence of ipsilateral refluxing blind megaureter.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Review Paper2013-03-30
10.5173/ceju.2013.03.art26
Clinical experience with once-daily tacrolimus in de novo kidney transplant recipients from living donors in Japan: -year follow up
Kenichiro Ishida, Shinichi Ito, Tomohiro Tsuchiya, Yoshinori Imanishi, Takashi Deguchi
We assessed our clinical experience with de novo kidney transplant recipients from living donors who received once-daily tacrolimus (OD TAC). In addition, we investigated tacrolimus pharmacokinetics and compared the dose of tacrolimus in de novo kidney transplant patients treated with OD TAC or twice-daily tacrolimus (BD TAC).

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Editorial Referring10.5173/ceju.2013.03.art27
Once- versus twice-daily tacrolimus: are the formulations equivalent?
Michał Ciszek

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Review Paper2013-11-14
10.5173/ceju.2013.03.art28
Urogenital disorders after pelvic ring injuries
Atom A. Ter-Grigorian, George R. Kasyan, Dmitry Y. Pushkar
The close anatomical relationship between the skeletal and connective systems of the pelvis, neurological and vascular structures and pelvic organs are the predisposing factors for structural and functional damages of the urogenital system.

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Editorial Referring10.5173/ceju.2013.03.art29
Urological implications of pelvic trauma
Cristian Persu

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Editorial Referring10.5173/ceju.2013.03.art30
We need to know the treatment urethral injuries
Thorsten H. Ecke

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Original Basic Research And Clinical Articles2013-07-05
10.5173/ceju.2013.03.art31
Transperitoneal laparoscopic pyeloplasty in the treatment of Ureteropelvic Junction Obstruction.
Juan Gómez Rivas, Sergio Alonso y Gregorio, María A. Portilla Eastmond, Jesús Cisneros Ledo, Luis Hidalgo Togores, Jesús Javier de la Pena Barthel
Laparoscopic pyeloplasty was first described by Schuessler. During the last decade, this technique has been developed in order to achieve the same results as open surgery, with lower rates of morbidity and complications. In this study we review our experience using laparoscopic pyeloplasty as the gold standard for the treatment of the ureteropelvic junction obstruction (UPJO).

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Case Report2013-07-19
10.5173/ceju.2013.03.art32
CASE REPORT: LAPAROSCOPIC URETERAL REIMPLANTATION IN THE RENAL TRANSPLANT
Sergio Alonso y Gregorio, Juan Gómez Rivas, Leslie Cuello Sánchez, Jesús Cisneros Ledo, Luis Hidalgo Togores, Jesús Javier de la Pena Barthel
We present what is to our knowledge, the first case of laparoscopic ureteral reimplantation reported in the renal transplant.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Editorial Referring10.5173/ceju.2013.03.art33
Sometimes the communications are of special value
Marcin Słojewski

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Author's Reply10.5173/ceju.2013.03.art34
Author's reply
Sergio Alonso y Gregorio, Juan Gómez Rivas

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Case Report2013-06-25
10.5173/ceju.2013.03.art35
Case report: A trial of prophylactic placement of ureteral catheters in a case of excision of a huge pelvic mass with incidental cystotomy
Hussein Warda
Ureteral injuries are one of the major complications following gynecologic surgeries. They are serious, troublesome and associated with significant morbidity. We present a case of a 8-year old obese female who presented with a very large pelvic mass. We attempted to use preoperative prophylactic bilateral ureteral catheters to prevent injury. A laparotomy was performed with removal of the large multi-lobulated pelvic mass, total abdominal hysterectomy, bilateral salpingo-oophorectomy, appendectomy and repair of an incidental cystotomy

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Original Basic Research And Clinical Articles2013-07-19
10.5173/ceju.2013.03.art36
Propionylcarnitine and methionine concentrations in newborns with hypospadias
Andrzej Kowal, Dariusz Mydlak, Mariusz Ołtarzewski, Anna Bauer, Ewa Sawicka, Kamil K. Hozyasz
Of interest is that factors like maternal diet can influence the risk of hypospadias-affected pregnancy. Increased propionylcarnitine (C3) is regarded as a biomarker of vitamin B12 deficiency. The retrospective study was undertaken to determine whether increased propionylcarnitine and low methionine in newborns are associated with hypospadias.

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Editorial Referring10.5173/ceju.2013.03.art37
Influence of maternal diet on the development of malformation of the external genitalia - Are we ready to make some recommendations?
Raimund Stein

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Case Report2013-05-18
10.5173/ceju.2013.03.art38
Congenital Giant Hydroureter Presenting as Abdominal Mass in an Infant
Tarun Dilip Javali, Prathvi Shetty, Nagaraj Harohally
Herein we present a case of a 7 months old baby girl, with left single system ectopic ureter, in whom the ureter was dilated to such an extent that it presented as an abdominal mass.

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Dear Colleagues!

Please forgive me for this somewhat reflective mood, but it is caused by the up- coming end of the 2015-2018 term of the PUA Executive Board. As you probably know, the Editor-in-Chief of the Central European Journal of Urology is appointed by the PUA Executive Board, which is why this introductory article is somewhat of a summary.

So then, for this reason, I would like to share some information about the development of the journal. The journal is developing very well. When analyzing the names of the authors, we can see that we are recognizable not only in Europe but also around the world. Urologists from large academic centers publish their articles in our journal. We operate on an "open access" basis and therefore do not charge any fees. This is undoubtedly an asset. An expression of this is the growing number of our citations. The CiteScore coefficient for the Central European Journal of Urology is currently 1.11, while last year it was 0.70. The systematic increase in citations year by year sets the stage to move us from Emerging Cites Sources and promote us to the Science Citation Index Expanded, managed by Clarivate Analytics, formerly Thomson Reuters, which is associated with the granting of the socalled "Impact Factor". I first submitted our journal in 2015 and the assessment, at that time made by Thomson Reuters, was that we should remain in the "waiting room", and therefore we were included in Emerging Sources Citation Index. I submitted my second request for re-assessment at the end of 2017 and I am currently awaiting an answer. I hope to get a positive decision.

Building a urological journal in Europe is not a simple task. We already have journals of recognized position and reputation, such as European Urology, European Urology Focus, as well as World Journal of Urology, Urologia Internationalis, Scandinavian Journal of Urology and International Urology and Nephrology. There are also newly created journals such as European Urology Oncology which has very strong support from the European Association of Urology. We must show that we are needed in Central Europe! We do not have anything to prove!

The standing of a scientific journal depends firstly on the quality of the materials submitted, that is from the authors' workshops. However, this is only one side of the coin!

The team of people who verifies submitted scientific materials is also very crucial. This is probably the most important thing that I would like to convey. Usually, I do not officially direct words of thanks to my colleagues, because I think that they consciously chose the tasks they carry out in their lives. At this point, however, at the end of the 2015-2018 term of the PUA Executive Board, I would like to thank Dr. Bartosz Dybowski, my assistant Editor-in-Chief, for the enormous amount of work and time devoted to the extremely professional preparation of each issue. His ex- pert knowledge and availability could be the envy of many a manager. Without the hard work of Dr. Dybowski, this journal would not look like it does today, and the choice of his person for this position was certainly the right one.

I would also like to personally thank our section editors for their hard work and input. Przemysław Adamczyk, Ewa Bres-Niewada, Stefan Buntrock, Abdullah Erdem Canda, Michał Ciszek, Olga Dolejšová, Simona Di Francesco, Jan Hrbáček, Kajetan Juszczak, George Kasyan, Daimantas Milonas, Maciej Salagierski and Przemysław Waliszewski have always stood up to the task. Dear Colleagues, I know how much you have done for the journal, I appreciate it, and I will always remember your commitment.

Nothing could be done without the huge backing of internationally recognized professionals, without which the magazine would not be in the right form and would not grow. The Consulting Editors and the Editorial Board are these advisory bodies that I would like to thank for their knowledgeable comments and support in making difficult decisions.

Also, I would like to recognize the Reviewers, who often work "behind the scenes" but are nonetheless extremely helpful. Their complete independence allows them to give us their wise and unbiased opinions. Thank you for your support during the entire 2015-2018 term.

In conclusion, it is my sincere hope that the journal will continue to develop even better and even more vigorously in the coming years.


Tomasz Drewa
Editor-in-Chief

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Corrigendum
The Editorial Office would like to inform all interested parties that in Central European Journal of Urology an article entitled "Efficacy of holmium laser urethrotomy and intralesional injection of Santosh PGI tetra-inject (Triamcinolone, Mitomycin C, Hyaluronidase and N-acetyl cysteine) on the outcome of urethral strictures" [Kumar S, Kishore L, Sharma AP, Garg N, Singh SK. Cent European J Urol. 2015; 68: 462-465] was published which is very similar to the article entitled "Efficacy of Optical Internal Urethrotomy and Intralesional Injection of Vatsala-Santosh PGI Tri-Inject (Triamcinolone, Mitomycin C, and Hyaluronidase) in the Treatment of Anterior Urethral Stricture" published in Advances in Urology [Kumar S, Garg N, Singh SK, Mandal AK. Adv Urol. 2014; 2014: 192710. doi: 10.1155/2014/192710. Epub 2014 Oct 1].

The authors of these articles did not inform the CEJU Editorial Office about the prior publication of an article with a similar subject matter nor did they refer to it in their References section.

The Editorial Office regrets the existing situation.