Archive issues
Author:
Title:
Keywords:
Newsletter
Enter your email:
Publications About the journal Submit manuscript CEJU Publication System Subscription Contact

2011 Vol. 64 No. 4

Review Paper2011-08-23
10.5173/ceju.2011.04.art1
Prostate Cancer Stem Cells
Hanna Romańska-Knight, Paul Abel
The Cancer Stem Cells (CSCs) hypothesis postulates that a minute subpopulation of cells is accountable for cancer initiation and progression. Unlike the stochastic and clonal evolution models, the CSC theory proposes that tumours are hierarchical and only the rare subset of cells at the top of the 'stemness hierarchy tree' are adequately 'equipped' biologically to initiate and drive tumourigenesis. CSCs have been implicated in various solid malignancies including prostate cancer (PCa), where their existence seems to provide an explanation for the failure of tumour eradicating therapies

FULL TEXT

Review Paper2011-08-16
10.5173/ceju.2011.04.art2
RECIPROCAL CROSS-TALK BETWEEN PROSTAGLANDIN E2 AND BONE IN PROSTATE CANCER: A CURRENT REVIEW.
Simona di Francesco, Pietro Castellan, Rossella Manco, Raffaele L. Tenaglia
In this review we analyzed the role of PGE2 as a possible regulator of bone metabolism and bone metastases in prostate cancer .Published studies were identified by searching computerized bibliographic systems from 1 January 2000 to 1 July 2011. PGE2 represent a key factor that modulate bone metabolism and bone metastatic disease in prostate cancer interacting with bone regulatory signals including the RANK/RANKL/OPG system and Wnt pathways. High concentrations of PGE2 exerts a prevalent stimulatory effect on osteoclastogenesis via OPG/RANK/RANKL axis activation and a inhibitory effect on osteoblastogenesis trough inhibition of Wnt pathway

FULL TEXT

Original Basic Research And Clinical Articles2011-08-17
10.5173/ceju.2011.04.art3
Factors Predicting Gleason Score 6 Upgrading After Radical Prostatectomy
Daimantas Milonas, Aivaras Grybas, Stasys Auskalnis, Inga Gudinaviciene, Ruslanas Baltrimavicius, Marius Kincius, Mindaugas Jievaltas
Prostate cancer Gleason score 6 is the most common score detected on prostatic biopsy. We analyzed the clinical parameters that predict the likelihood of Gleason score upgrading after radical prostatectomy.

FULL TEXT

Original Basic Research And Clinical Articles2011-08-08
10.5173/ceju.2011.04.art4
Outcome of surgery in locally advanced pT3a prostate cancer.
Daimantas Milonas, Ruslanas Baltrimavicius, Aivaras Grybas, Inga Gudinaviciene, Darius Trumbeckas, Marius Kincius, Stasys Auskalnis, Mindaugas Jievaltas
The aim of this study is to present the oncologic outcomes and to determine prognostic parameters of overall (OS), cancer specific survival (CSS), disease progression free survival (DPFS) and biochemical progression free survival (BPFS) after surgery for pT3a prostate cancer (PCa).

FULL TEXT

Original Basic Research And Clinical Articles2011-08-10
10.5173/ceju.2011.04.art5
Urinary incontinence after radical prostatectomy - experience of last 00 cases.
Roman Sosnowski, Michał Szymański, Jan Karol Wolski, Tomasz Nadolski, Tomasz Kalinowski, Tomasz Demkow, Piotr Peczkowski, Małgorzata Pilichowska, Marcin Ligaj, Wojciech Michalski
Radical prostatectomy (RP) is a recognized treatment method of organ-confined prostate cancer. Among post-surgery complications urinary incontinence is a major one.
The aim of the study was to determine the incontinence rate after RP and to analyze factors that might affect it.

FULL TEXT

Original Basic Research And Clinical Articles2011-07-28
10.5173/ceju.2011.04.art6
The impact of adjuvant therapy in patients with biochemical recurrence on prostate cancer progression and mortality 5 years after radical prostatectomy
Mieczysław Fryczkowski, Piotr Bryniarski, Maciej Szczębara, Marian Suchodolski, Andrzej Paradysz
The clinical significance of biochemical recurrence (BCR) after radical prostatectomy (RP) due to prostate cancer (Pca) is not unambiguous, sometimes being independent from the real progression. BCR is followed by the greater risk of adverse previsions and almost always results in necessity of the adjuvant therapy (AT) implementation.
Aim: The aim of the following study is to examine the impact of AT in patients with BCR on Pca progression and mortality 5 years after RP.

FULL TEXT

Original Basic Research And Clinical Articles2011-09-12
10.5173/ceju.2011.04.art7
IMPACT OF POSITIVE SURGICAL MARGINS ON BIOCHEMICAL RELAPSE AFTER RADICAL RETROPUBIC PROSTATECTOMY (RRP)
Pedro Bargao Santos, Bruno Graça, Miguel Lourenço, Manuel Ferreira Coelho, Fernando Ribeiro, Júlio Fonseca, A. Pepe Cardoso, Joao Varregoso, Fernando Ferrito, Francisco Carrasquinho Gomes
RP technique continues the major treatment option for men with potential cure and life expectancy exceeding 10 years.Objectives:To access the impact of PSM on BR. To identify PSM risk factors. To clarify the factors involved in BR in the absence of PSM.

FULL TEXT

Original Basic Research And Clinical Articles2011-08-17
10.5173/ceju.2011.04.art8
The credibility of a questionnaire on smoking in patients with bladder cancer on the basis of the urine cotinine level. Preliminary report.
Jarosław Leszniewski, Ewa Pufal, Zbigniew Wolski
Confirmed an association of bladder cancer and smoking.
To assess the reliability of subjects history of smoking, and assess compliance with recommendations of quitting smoking.

FULL TEXT

Original Basic Research And Clinical Articles2011-09-15
10.5173/ceju.2011.04.art9
Efficacy of combination therapy with tamsulosin and zolpidem on nocturia in patients with benign prostatic hyperplasia
Kousei Miwa, Yoshinori Nishino, Mina Kikuchi, Takako Masue, Yoji Moriyama, Takashi Deguchi
We examined the efficacy of combination therapy with α1- blocker tamsulosin and hypnotic zolpidem in patients who had suffered from sleep disturbance associated with nocturia.

FULL TEXT

Short Communications (Preliminary Results And Mini-Reviews)2011-08-10
10.5173/ceju.2011.04.art10
Vesicourethral anastomosis using V-Loc™ barbed suture during robot-assisted radical prostatectomy
Stephen Chapman, Rafał Turo, William Cross
In Europe, localised prostate cancer is increasingly treated by robot-assisted radical prostatectomy. This minimally invasive procedure is technically evolving, benefiting both the patient and surgeon. One of the final steps of the operation is the formation of a watertight vesicourethral anastomosis (VUA). A suboptimal anastomosis can lead to serious consequences, including acute urinary leak, ileus, prolonged hospitalisation and catheterisation, urethral stricture and urinary incontinence. It is therefore highly desirable to develop a simple, reproducible and dependable technique for VUA formation

FULL TEXT

Review Paper2011-08-22
10.5173/ceju.2011.04.art11
BLADDER AUGMENTATION AND CONTINENT URINARY DIVERSION IN BOYS WITH POSTERIOR URETHRAL VALVES
Małgorzata Baka-Ostrowska
Posterior urethral valve (PUV) is a condition that leads to characteristic changes in the bladder and upper tract. Dysfunction of the bladder such as hyperreflective, hypertonic, small capacity bladder, sphincter incompetence and/or myogenic failure should be adequately treated. Poor compliance/small bladder could be treated by anticholinergics but most probably will need bladder augmentation. Although bladder reconstruction with gastrointestinal segments can be associated with multiple complications, such as metabolic disorders, calculus formation, mucus production, enteric fistulas and potential for malignancy, enterocystoplasty is still the gold standard

FULL TEXT

Review Paper2011-08-18
10.5173/ceju.2011.04.art12
Pediatric single port transumbilical nephrectomy and nephrourerectomy.
Wiesław Urbanowicz, Janusz Sulisławski, Michał Wolnicki
To present seven cases of single incision laparoscopic nephrectomy and nephroureterectomy in children as a recent videoscopic innovation.

FULL TEXT

Original Basic Research And Clinical Articles2011-09-02
10.5173/ceju.2011.04.art13
Analysis of single-institutional experience of 000 cases of synthetic midurethral slings used for treatment of female urinary incontinence
Dmitri Pushkar, George Kasyan, Michail Gvozdev, Roman Sosnowski
This study summarized our experience of treatment on 1081 women with SUI using mid-urethral slings.

FULL TEXT

Original Basic Research And Clinical Articles2011-08-08
10.5173/ceju.2011.04.art14
Immunohistochemical detection of angiotensin AT and AT2 receptors in prostate cancer
Marek Pawlikowski, Radosław Minias, Marek Sosnowski, Krzysztof W. Zieliński
The human prostate gland contains all the compounds of the renin-angiotensin system(RAS), including AT1 and AT2 angiotensin receptors. The role of local RAS in the prostate pathology is recently discussed. The aim of the present study was the evaluation of AT1 and AT2 expressions in human prostate cancers.

FULL TEXT

Original Basic Research And Clinical Articles2011-09-15
10.5173/ceju.2011.04.art15
Prostate epithelial stem cells are resistant to apoptosis after alpha-antagonist treatment. The impact for BPH patients
Anna Bajek, Łukasz Pokrywka, Zbigniew Wolski, Robert Dębski, Tomasz Drewa
Induction of apoptosis in prostatic epithelial cells by doxazosin, terazosin and prozosin has been well documented. However, the biochemical pathways of doxazosin action is still unclear. Aforementioned drugs should lead to decrease of prostate volume, although this effect was never observed in patients suffering from BHP after treatment with α1-antagonists. Probably, it is connected with cancer stem cells' resistance on chemotherapeutic agents. The aim of this study was to compare incidence of apoptosis induced by doxazosin in progenitor and differentiated cells isolated from human prostate epithelium.

FULL TEXT

Case Report2011-08-08
10.5173/ceju.2011.04.art16
Intratesticular epidermoid cyst; is radiological diagnosis enough?
Michał Sut, Ali Thwaini, Brendan Devlin, Maeve Dooher, Franz Schattka
Intratesticular epidermoid cysts are rare solid tumour-like lesions. They constitute 1% of all testicular tumours. Major advances have been achieved during the last decades, shifting the management of epidermoid cysts to a more conservative approach.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

FULL TEXT

Case Report2011-09-07
10.5173/ceju.2011.04.art17
Management of bladder neck leiomyoma in pregnancy - case report.
Krzysztof Tupikowski, Paweł Szewczyk, Tomasz Szydełko, Agnieszka Hałoń, Marcin Polok, Janusz Dembowski, Romuald Zdrojowy
A 29-year-old primigravida was admitted to the urology ward with an acute urinary retention. The patient underwent cystoscopy, MRI and tumor biopsy and was diagnosed with a bladder neck leiomyoma that obstructed urine outflow. Subsequent to a cesarean section, a successful transurethral resection was performed. Diagnostic complexity in the pregnant patient, clinical course and outcome are described. One year after successful treatment both, mother and daughter are in good condition.

FULL TEXT

Case Report2011-07-28
10.5173/ceju.2011.04.art18
Scrotal hematoma resulting from extracorporeal shock wave lithotripsy for a renal calculus: a sign of retroperitoneal hemorrhage
Raja Devanathan, Darren J. Katz, Lachlan J. Dodds
We report a rare case of a patient presenting with scrotal hematoma post Extracorporeal Shock Wave Lithotripsy (ESWL), in association with retroperitoneal hemorrhage. We propose a mechanism for the formation of scrotal hematoma, and its importance as a sign of retroperitoneal hemorrhage.

FULL TEXT

Case Report2011-09-20
10.5173/ceju.2011.04.art19
Partial segmental thrombosis of the corpus cavernosum-case report
Jarosław Głuchowski, Adam Bławat, Janusz Kordasz, Artur Jeliński, Anna Łazarczyk
The case of a 32 years old man with perineal pain and local swelling was presented. Partial segmental thrombosis of corpus cavernosum was diagnosed and treated conservatively with systemic anticoagulants. Conservative management proved to be safe and successful therapeutic option in partial thrombosis of the corpus cavernosum.

FULL TEXT

Case Report10.5173/ceju.2011.04.art20
Primary cancer of the anterior urethra in a male patient
Zbigniew Wolski, Janusz Tyloch, Patryk Warsiński

FULL TEXT

Dear Friends,

I would like to wish you all a very Merry Christmas and Happy New Year 2018! I hope that this holiday season will bring you time to relax and reflect upon the past year.

The medical profession brings many possibilites for new ventures and in a certain way predisposes us to this.

We as doctors have many important roles to fulfill, usually simultaneously, such as those of: therapists, operators, scientists, managers, lecturers, publishers, editors, authors, and association members. The number of our endeavours is undoubtedly larger and continues to impress me.

Please forgive me for a short personal digression. Once, I met the children of a prominent surgeon and scientist, who was committed to his patients and whose achievements I had read about in journals. I asked them what kind of a person he was on a daily basis and what did he pass on to them, the next generation? "Dad? He went to work early in the morning, came home late at night, and on Sundays he needed his rest. We barely knew him".

Therefore, I would like to wish you all of the best and that during this holiday season you are able to spend quality time with your families and those closest to you. In time, everything will pass; our successors and new methods and techniques will arrive. Grateful patients will soon forget, and only we will remain, in the memories of our loved ones.


Kindest regards,
Tomasz Drewa
Editor-in-Chief,
Central European Journal of Urology

Menu

About the journal

Subscription

Contact

Publications

Ahead of print

Current issue

Users

Submit manuscript

Instructions for authors

CEJU Publication System

© Copyright by Polish Urological Association

Logo CEJU